Dr. Loudon's Vaccine Guide
Vaccines save lives...
but they can also do harm.

When Vaccines Are A Must?
Vaccines Are Necessary To Protect Your Puppy Against Life-Threatening Illnesses Such As Parvovirus, Distemper, and Rabies
The Difference Between Core and Non-Core Vaccines
Non-Core Vaccines
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Bordetella (kennel cough)
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Lyme Disease
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Leptospirosis 4-way (this is sometimes included in combination vaccines with core vaccines, but it is a non-core vaccine and should be considered separately)
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Canine Influenza
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Parainfluenza
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Adenovirus
Core Vaccines
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Rabies
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Parvovirus
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Distemper
NON-CORE VACCINES
These are a group of vaccines that are not recommended for every dog and are based on the dog’s lifestyle, location, genetic history, general health, and individual exposure risk.
Non-core vaccines are generally less effective, lasting less than 12 months, and are known to cause more vaccine reactions. These vaccines require yearly boosters.

Leptospirosis
Leptospirosis is a disease caused by Leptospira bacteria, found worldwide in soil and water. This zoonotic disease can affect both animals and humans, though human cases in the United States typically result from water activities rather than contact with infected pets. However, transmission from pets is possible, though rare.
Risk Factors for Dogs
Dogs may be at higher risk if they:
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Drink from or have exposure to rivers, lakes, or streams
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Roam rural areas with potential exposure to infected wildlife or farm animals
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Have contact with wild animals or rodents, even in urban settings
Leptospirosis is more prevalent in warm, rainy regions but can occur anywhere.
Leptospirosis Vaccine Considerations
The World Small Animal Veterinary Association (WSAVA) notes:
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The leptospirosis vaccine offers only short-term immunity (3-12 months).
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Vaccine effectiveness varies by strain, offering limited protection against certain strains.
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This vaccine is linked to more adverse reactions than other dog vaccines.
Efficacy and Immunity
The vaccine provides limited immunity, often lasting only a few months, with minimal long-term memory. While it may reduce disease symptoms, it may not fully prevent infection or bacterial shedding, especially after six months. If the prevalent strain in your area differs from the vaccine strain, the vaccine’s protection will be minimal.
Human Vaccine for Leptospirosis
Currently, no vaccine exists for humans. The Lancet (2003) highlights challenges in human vaccine development:
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Killed bacterial vaccines have severe side effects.
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Protection tends to be short-term and may be incomplete.
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Regional variations in Leptospira strains complicate universal vaccine effectiveness.
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Risks of autoimmune reactions, such as uveitis, are significant.
Given the high rate of side effects and limited efficacy in both animals and humans, it's worth questioning the routine vaccination of dogs for leptospirosis.

Lyme Disease
Lyme disease, caused by Borrelia burgdorferi bacteria, is transmitted to animals and humans through the bite of infected deer ticks (also known as black-legged ticks). Although Lyme disease can affect dogs, horses, and possibly cats, most dogs that test positive do not show symptoms. When symptoms do occur, they often include lameness, swollen lymph nodes, joint swelling, fatigue, and appetite loss.
Considerations for the Lyme Vaccine in Dogs
The Lyme vaccine is generally not recommended for dogs due to limited and inconsistent efficacy. Unlike core vaccines that prevent severe, life-threatening diseases, the Lyme vaccine does not consistently prevent infection or symptoms in all dogs, and it requires frequent boosters to maintain limited immunity.
Alternative Prevention Strategies
Effective management of Lyme disease risk can often be achieved with consistent tick prevention measures:
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Use natural tick repellents and conduct daily tick checks.
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Keep outdoor spaces free of tall grasses where ticks thrive.
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Promptly remove ticks to prevent transmission.
For dogs in Lyme-endemic areas, a combination of regular prevention and prompt tick removal is often more effective and avoids the potential side effects associated with the Lyme vaccine.

Bordetella Bronchiseptica
(Kennel Cough)
Kennel cough, or canine infectious tracheobronchitis, is a highly contagious respiratory illness that spreads easily in environments where dogs gather, like boarding facilities, dog parks, and daycare centers. It is transmitted through airborne droplets, direct contact, and shared items (e.g., food bowls). Most cases are mild and treatable, but puppies, immunocompromised dogs, and those in poor living conditions may be at risk for more severe illness, such as pneumonia.
Symptoms of Kennel Cough
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Persistent, honking cough
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Nasal discharge
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Lethargy
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Decreased appetite
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Fever
Treatment
Most adult dogs recover without medication, as kennel cough often resolves on its own. Antibiotics can be effective for young or vulnerable dogs if treated early. Severe cases are rare and typically occur in puppies or immunocompromised dogs.
Bordetella Vaccine Considerations
The World Small Animal Veterinary Association (WSAVA) notes that the kennel cough complex includes multiple pathogens, and vaccination may not prevent infection completely, as kennel cough affects the localized respiratory tract. The intranasal Bordetella vaccine, often combined with parainfluenza, is commonly used but can cause mild, temporary side effects like coughing and nasal discharge. In rare cases, it has been linked to outbreaks in kennels.
Alternatives
If your dog's risk for kennel cough is low and your groomer, boarding facility, or veterinarian requires the Bordetella vaccine, consider discussing alternative options or a waiver if appropriate for your dog’s lifestyle and health status.
In summary, non-core vaccines…
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Must be decided upon, based on the individual patient’s risks. For example, a toy breed dog that is mainly indoors should never be vaccinated with non-core vaccines.
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Are more dangerous and are known to cause more reactions in dogs.
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Are generally not very effective.
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Do not provide “protection” for very long.
CORE VACCINES
A core vaccine is an essential immunization recommended for all puppies and dogs, regardless of lifestyle or location, due to the high risk and severity of the diseases it prevents. Core vaccines protect against highly contagious and potentially fatal diseases that pose significant health risks to both pets and humans. For puppies, these include parvovirus, distemper, and rabies, as each targets serious illnesses that are widespread and can be transmitted through everyday exposure.

Parvo
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Parvovirus is a highly contagious virus that mostly affects young, unvaccinated dogs.
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It causes severe diarrhea, vomiting, abdominal pain, and anorexia. The symptoms are severe and often lead to death.
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Infected puppies often require long hospital stays in order to recover fully.
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Parvo lives well in the environment, both indoors and outside. It can survive indoors and outdoors for months to years, especially in dark, moist environments.

Distemper
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Canine distemper is a contagious and serious disease caused by a virus that affects the respiratory, gastrointestinal, and sometimes even the nervous systems of puppies and dogs.
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Symptoms often start with the respiratory system which includes nasal and ocular discharge, coughing, and eventually difficulty breathing due to pneumonia. Symptoms then may progress to the gastrointestinal and neurological systems.
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The virus can also be found in wildlife such as foxes, wolves, coyotes, raccoons, skunks, mink, and ferrets and has been reported in lions, tigers, leopards, and other wild cats as well as seals.

Rabies
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Transmission-The virus does not survive outside of the infected host very long, so direct contact with fresh secretions is required for transmission.
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This infection has nearly 100% mortality, therefore, preventing it in pets becomes crucial to preventing it in people.
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State law governs the frequency required for this vaccine.
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Some states allow for medical exemptions from rabies vaccines for pets who are ill or have had a prior adverse reaction.
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Rabies vaccinations should never be given at the same time as another vaccine. They should be given alone, separated from all other vaccinations by at least three weeks.
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Since rabies is the only vaccine required by law, it should be the only repetitive vaccine you give your dog.
VACCINES SAVE LIVES.
BUT THEY CAN ALSO SHORTEN THEM.
The Dangers of Over-Vaccination
If an animal which already has a significant level of antibodies to a particular virus where to be vaccinated, it would not respond with a significant increase in antibody titer, but instead has the potential to develop a hypersensitivity to vaccine components
The Purdue Vaccine Study in the 1990s showed autoimmunity developing in dogs after a single vaccine, whereas none of the dogs in the unvaccinated group did so.
Over-Vaccination Can Lead To
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Autoimmune diseases
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Cancer
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Life-threatening allergic reactions
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Seizures
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Reproductive disorders
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Chronic diseases such as arthritis, diabetes, and Cushing's disease.
Titer Testing
Bloodwork done to test the level of antibodies in the blood to assess sufficient immunity to a disease. Antibodies are produced when an antigen (like a virus or bacteria) provokes a response from the immune system
How often? I recommend it every 3-5 years. Challenge tests show that successful vaccination against core vaccines gives most animals at least 7-15 years of immunity.
My Vaccine Protocol
(may be tailored to the individual dog)
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9-10 weeks-distemper/parvo combo
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13-14 weeks-distemper/parvo combo or titer
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17-18 weeks-distemper/parvo titer. If titer is low then repeat distemper/parvo vaccine. (unlikely to be low)
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6-12 months - rabies vaccine. Discuss rabies detoxifying remedies with your local holistic vet to be given prior and post vaccination. Check your state laws.
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1.5 years old TITER for distemper/parvo (preferred) or give 3 year distemper/parvo. Give the 3 year rabies vaccine. Spread the rabies vaccine and distemper/parvo at least 3-4 weeks apart.
Perform vaccine antibody titers for distemper and parvovirus every three-five years thereafter. Vaccinate for rabies virus according to your state’s law. Find out if a written waiver from the primary care veterinarian and a sufficient titer is adequate in your state.
Treatment For Vaccine Reactions
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If your puppy is exhibiting mild symptoms you can try giving:
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Quercetin
Quercetin is effective in helping allergic reaction symptoms and is known as “Nature’s Benadryl.” Quercetin supplements should be given on an empty stomach. -
Nettles
Nettles contain histamines and quercetin, which stimulate the body to protect itself from allergens and boost anti-allergy effects. Here is a link to a Nettle tincture I recommend. -
Both are good ones to have in your medicine cabinet!
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If your puppy’s symptoms come one quickly and severely then give a dose of each of these or Benadryl 1 mg/lb and head straight to the ER. Benadryl dosing example, 10lbs dog receives 10mg of Benadryl. Can be give every 8 hours.
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Steroids are sometimes necessary for severe reactions. Your vet may give an injection IV and then send you home with a few doses if the allergic reaction is severe.
I Do Not Recommend Dogs Be Vaccinated If They:
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Have a history of immune-mediated disease
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Are currently sick or have a fever
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Are on medications for acute illness
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Suffer from chronic disease (diabetes, cushing's disease, severe arthritis, etc.)
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Have had adverse reactions to vaccines in the past
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Are over 6 years old
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Have a fever at the time of vaccines
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Have a seizure history
Know The Symptoms of A Vaccine Reaction:
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Severe Itchiness
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Hives over the face and body
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Reddened skin
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Facial swelling
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Vomiting
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Acute lethargy
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Crying out in pain
Here Are Some Options For Titering
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Dr. Jean Dodd offers inexpensive titer testing at her website, https://hemopet.org/titer-testing/
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Vaccicheck
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TiterCHEK
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Your veterinarian can also send out titers however, it is usually more expensive.
How To Safely Vaccinate Your Dog
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Give Core vaccines only
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Do not start earlier than 9 weeks of age
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ONLY 2 rounds of puppy vaccines, at most, then titer
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Be sure your dog is in a healthy state prior to vax
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NEVER give if your dog has had a vaccine reaction
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Not more than one vaccine at a time
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Spread apart at least 3 wks
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Vaccines must be given as far down on back limbs as possible
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Have your vet give them in front of you
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Look at the sticker/bottle and make sure there aren’t extra letters
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Monitor for reactions
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Administer a homeopathic vaccine detox